Fluid resuscitation: Computer simulation and animal experiments

Inon Dagan, Michal Gabay, Ofer Barnea*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

The purpose of this study was to investigate the hemodynamic system in hemorrhagic shock and to estimate the effects of different infusion fluids and rates on the recovery of the bleeding patient. A mathematical model of the hemodynamic system was developed including fluid transfer to and from the interstitium for different types of fluids. The model was used to test different hemorrhagic shock conditions and different infusion conditions. To validate the model, a series of animal experiments was performed. The computer simulation followed successfully experimental data collected in five different experiments. Thus, it may now serve as an advanced tool for evaluating and analyzing effects of different fluids and optimize fluid regimen.

Original languageEnglish
Title of host publication29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
PublisherIEEE Computer Society
Pages2992-2995
Number of pages4
ISBN (Print)1424407885, 9781424407880
DOIs
StatePublished - 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: 23 Aug 200726 Aug 2007

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)0589-1019

Conference

Conference29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Country/TerritoryFrance
CityLyon
Period23/08/0726/08/07

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