Fine structure of Sertoli and Leydig cells in azoospermic human testis

N. Livni, Z. Palti, S. Segal, A. Laufer

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Testicular biopsy specimens taken from 7 patients, 31 to 41 yr old, with azoospermia were studied by electon microscopy. The patients displayed well-developed secondary sex characteristics, normal endocrine functions (determined by circulating and urinary gonadotropin levels), and normal plasma testosterone and T4 levels. It was clear that the infertility was directly related to a primary testicular defect. The possibility was considered of a relation between the annulate lamellae in the Sertoli cells and the azoospermia. In the Leydig cells, intranuclear and intracytoplasmic paracrystalline inclusions were observed and a relation with the Reinke crystalloids is considered.

Original languageEnglish
Pages (from-to)442-445
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Issue number8
StatePublished - 1977
Externally publishedYes


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