Fine needle aspiration biopsy in patients with diffusely enlarged spleens

Michael Lishner; Ruth Lang; Yali Hamlet; Elizabeth Halph; Zeev Steiner; J. Radnay; Mordchai Ravid

doi:10.1159/000333737

Fine needle aspiration biopsy in patients with diffusely enlarged spleens

Michael Lishner^*, Ruth Lang, Yali Hamlet, Elizabeth Halph, Zeev Steiner, J. Radnay, Mordchai Ravid

^*Corresponding author for this work

Clinical Departments

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Abstract

OBJECTIVE: To evaluate the diagnostic value and potential risk of fine needle aspiration biopsy (FNAB) of the spleen in patients with diffuse splenomegaly due to an undetermined cause. STUDY DESIGN: Retrospective evaluation of the medical records and cytologic material from 58 patients on whom FNAB was performed between 1967 and 1993. RESULTS: Sixty-five FNABs were performed on 58 patients. Lymphoproliferative diseases were found in six; in four additional cases, metastatic adenocarcinoma, sarcoidosis, Candida albicans and enterococcal infection were demonstrated. The remaining 55 biopsies either showed normal splenic tissue or were nondiagnostic. No complications were recorded. CONCLUSION: Splenic FNAB may be useful in some patients with diffuse splenomegaly. The diagnostic yield is rather low. The procedure, however, is simple, safe and well tolerated.

Original language	English
Pages (from-to)	196-198
Number of pages	3
Journal	Acta Cytologica
Volume	40
Issue number	2
DOIs	https://doi.org/10.1159/000333737
State	Published - 1996

Keywords

Aspiration biopsy
Splenic diseases

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10.1159/000333737

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title = "Fine needle aspiration biopsy in patients with diffusely enlarged spleens",

abstract = "OBJECTIVE: To evaluate the diagnostic value and potential risk of fine needle aspiration biopsy (FNAB) of the spleen in patients with diffuse splenomegaly due to an undetermined cause. STUDY DESIGN: Retrospective evaluation of the medical records and cytologic material from 58 patients on whom FNAB was performed between 1967 and 1993. RESULTS: Sixty-five FNABs were performed on 58 patients. Lymphoproliferative diseases were found in six; in four additional cases, metastatic adenocarcinoma, sarcoidosis, Candida albicans and enterococcal infection were demonstrated. The remaining 55 biopsies either showed normal splenic tissue or were nondiagnostic. No complications were recorded. CONCLUSION: Splenic FNAB may be useful in some patients with diffuse splenomegaly. The diagnostic yield is rather low. The procedure, however, is simple, safe and well tolerated.",

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author = "Michael Lishner and Ruth Lang and Yali Hamlet and Elizabeth Halph and Zeev Steiner and J. Radnay and Mordchai Ravid",

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T1 - Fine needle aspiration biopsy in patients with diffusely enlarged spleens

AU - Lishner, Michael

AU - Lang, Ruth

AU - Hamlet, Yali

AU - Halph, Elizabeth

AU - Steiner, Zeev

AU - Radnay, J.

AU - Ravid, Mordchai

PY - 1996

Y1 - 1996

N2 - OBJECTIVE: To evaluate the diagnostic value and potential risk of fine needle aspiration biopsy (FNAB) of the spleen in patients with diffuse splenomegaly due to an undetermined cause. STUDY DESIGN: Retrospective evaluation of the medical records and cytologic material from 58 patients on whom FNAB was performed between 1967 and 1993. RESULTS: Sixty-five FNABs were performed on 58 patients. Lymphoproliferative diseases were found in six; in four additional cases, metastatic adenocarcinoma, sarcoidosis, Candida albicans and enterococcal infection were demonstrated. The remaining 55 biopsies either showed normal splenic tissue or were nondiagnostic. No complications were recorded. CONCLUSION: Splenic FNAB may be useful in some patients with diffuse splenomegaly. The diagnostic yield is rather low. The procedure, however, is simple, safe and well tolerated.

AB - OBJECTIVE: To evaluate the diagnostic value and potential risk of fine needle aspiration biopsy (FNAB) of the spleen in patients with diffuse splenomegaly due to an undetermined cause. STUDY DESIGN: Retrospective evaluation of the medical records and cytologic material from 58 patients on whom FNAB was performed between 1967 and 1993. RESULTS: Sixty-five FNABs were performed on 58 patients. Lymphoproliferative diseases were found in six; in four additional cases, metastatic adenocarcinoma, sarcoidosis, Candida albicans and enterococcal infection were demonstrated. The remaining 55 biopsies either showed normal splenic tissue or were nondiagnostic. No complications were recorded. CONCLUSION: Splenic FNAB may be useful in some patients with diffuse splenomegaly. The diagnostic yield is rather low. The procedure, however, is simple, safe and well tolerated.

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Fine needle aspiration biopsy in patients with diffusely enlarged spleens

Abstract

Keywords

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