Finally, Archaea Get Their CRISPR-Cas Toolbox

Uri Gophna; Thorsten Allers; Anita Marchfelder

doi:10.1016/j.tim.2017.03.009

Finally, Archaea Get Their CRISPR-Cas Toolbox

Uri Gophna, Thorsten Allers, Anita Marchfelder^*

^*Corresponding author for this work

Biotechnology

Research output: Contribution to journal › Short survey › peer-review

Abstract

The majority of archaea encode CRISPR-Cas systems but only a few CRISPR-Cas-based genetic tools have been developed for organisms from this domain. Nayak and Metcalf have harnessed a bacterial Cas9 protein for genome editing in Methanosarcina acetivorans, enabling efficient gene deletion and replacement.

Original language	English
Pages (from-to)	430-432
Number of pages	3
Journal	Trends in Microbiology
Volume	25
Issue number	6
DOIs	https://doi.org/10.1016/j.tim.2017.03.009
State	Published - Jun 2017

Keywords

CRISPR-Cas
Cas9
HDR
MMEJ
NHEJ
archaea

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tim.2017.03.009

Cite this

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abstract = "The majority of archaea encode CRISPR-Cas systems but only a few CRISPR-Cas-based genetic tools have been developed for organisms from this domain. Nayak and Metcalf have harnessed a bacterial Cas9 protein for genome editing in Methanosarcina acetivorans, enabling efficient gene deletion and replacement.",

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Finally, Archaea Get Their CRISPR-Cas Toolbox

Abstract

Keywords

UN SDGs

Access to Document

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