Fibrous dysplasia and cherubism as an hereditary familial disease

Y. Zohar, R. Grausbord, F. Shabtai, Y. Talmi

Research output: Contribution to journalArticlepeer-review


Five cases of dysplasia of the jaws in one family which has been under our observation since 1970 are reported. The disease appeared as a mixed display of jaw lesions, in some members as fibrous dysplasia and in others as cherubism. We were able to trace the disorder through an unbroken line of four generations, and thus to demonstrate autosomal dominant inheritance. Cytogenetic analysis performed on three members of this family revealed a significantly increased rate of chromosomal breakage.

Original languageEnglish
Pages (from-to)340-344
Number of pages5
JournalJournal of Cranio-Maxillo-Facial Surgery
Issue number8
StatePublished - 1989
Externally publishedYes


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