Abstract
The liver is the most common metastatic route of pancreatic cancer. Early recruitment of granulin-secreting inflammatory monocytes to the liver is now shown to reprogram hepatic stellate cells into myofibroblasts that modulate the liver microenvironment to support the growth of metastasizing tumour cells.
Original language | English |
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Pages (from-to) | 465-466 |
Number of pages | 2 |
Journal | Nature Cell Biology |
Volume | 18 |
Issue number | 5 |
DOIs | |
State | Published - 1 May 2016 |
Funding
Funders | Funder number |
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Wellcome Trust | 102521 |
Not added | MR/L000512/1 |