Fibrin sealant in surgery of patients with a hemorrhagic diathesis

U. Martinowitz, S. Schulman

Research output: Contribution to journalArticlepeer-review


The utilization of fibrin sealants in patients with hemostatic disorders has hitherto been very limited. Our experiences from 40 major and 8 minor surgical procedures, 10 circumcisions and 118 tooth extractions in 106 patients with hemophilia A, B or von Willebrand's disease, almost exclusively of the severe form, respectively, demonstrate the benefits regarding reduction of blood loss and requirements for systemic replacement therapy. The literature on the use of fibrin sealants in this group of patients, which mainly concerns dental procedures, is reviewed and compared with our data. The importance of the composition of the glue is also discussed in detail.

Original languageEnglish
Pages (from-to)486-492
Number of pages7
JournalThrombosis and Haemostasis
Issue number1
StatePublished - 1995
Externally publishedYes


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