Fetal pleural effusion: The risk of fetal trisomy

R. Achiron*, A. Weissman, S. Lipitz, S. Mashiach, B. Goldman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Our objective was to review the association between fetal pleural effusion (FPE) and fetal aneuploidy. We conducted a retrospective survey of pregnant women who presented to our ultrasonographic unit between 1990 and 1991, and in whom the diagnosis of FPE was reached. All fetuses had karyotype investigation and a complete ultrasonographic search for associated anomalies. Six cases of FPE were identified. Trisomy 21 was found in 2 (33%). The English literature was reviewed and an additional 147 cases with FPE were collected, among them 6 cases of trisomy 21 and 1 of monosomy 45X. In this accumulated series the risk of aneuploidy in a fetus with an incidental finding of FPE was 5.8% (9 of 153), thus warranting a karyotype study.

Original languageEnglish
Pages (from-to)153-156
Number of pages4
JournalGynecologic and Obstetric Investigation
Issue number3
StatePublished - 1995
Externally publishedYes


  • Fetal pleural effusion
  • Trisomy


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