Feasibility, safety, and effectiveness of a mobile application in cardiac rehabilitation

Irene Nabutovsky, Saar Ashri, Amira Nachshon, Riki Tesler, Yair Shapiro, Evan Wright, Brian Vadasz, Amir Offer, Liza Grosman-Rimon, Robert Klempfner

Research output: Contribution to journalArticlepeer-review


Background: Cardiac rehabilitation (CR) is underutilized globally despite evidence of clinical benefit. Major obstacles for wider adoption include distance from the rehabilitation center, travel time, and interference with daily routine. Tele-cardiac rehabilitation (tele-CR) can potentially address some of these limitations, enabling patients to exercise in their home environment or community. Objectives: To evaluate the clinical and physiological outcomes as well as adherence to tele-CR in patients with low cardiovascular risk and to assess exercise capacity, determined by an exercise stress test, using a treadmill before and following the 6-month intervention. Methods: A total of 22 patients with established coronary artery disease participated in a 6-month tele-CR program. Datos Health (Ramat Gan, Israel), a digital health application and care-team dashboard, was used for remote monitoring, communication, and management of the patients. Results: Following the 6-month tele-CR intervention, there was significant improvement in exercise capacity, assessed by estimated metabolic equivalents with an increase from 10.6 ± 0.5 to 12.3 ± 0.5 (P = 0.002). High-density lipoproteins levels significantly improved, whereas low-density lipoproteins, triglyceride, glycosylated hemoglobin, and systolic and diastolic blood pressure levels were not significantly changed. Exercise adherence was consistent among patients, with more than 63% of patients participating in a moderate intensity exercise program for 150 minutes per week. Conclusions: Patients who participated in tele-CR adhered to the exercise program and attained clinically significant functional improvement. Tele-CR is a viable option for populations that cannot, or elect not to, participate in center-based CR programs.

Original languageEnglish
Pages (from-to)357-363
Number of pages7
JournalIsrael Medical Association Journal
Issue number6
StatePublished - Jun 2020


  • Cardiac rehabilitation
  • Cardiovascular disease
  • Coronary artery disease
  • Mobile application
  • Tele-cardiac rehabilitation (tele-CR)


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