Fatal poisoning from nicotiana glauca leaves: Identification of anabasine by gas-chromatography/mass spectrometry

Nissim Mizrachi, Shlomo Levy, Zafrir Goren

Research output: Contribution to journalArticlepeer-review

Abstract

Death of a worker occurred after ingestion of unknown amounts of Nicotiana glauca G leaves. The leaves were cooked after having been mistakenly considered to be spices of a type which grow in Thailand. After ingestion, two Thai workers collapsed, one with asystolia. Resuscitation efforts were successful only for one of the victims. A GC/MS method was used for the identification of anabasine as the main constituent in the leaves, food extract, blood, and the urine of the deceased. Lacking a standard, it was necessary to interpret the GC/MS spectrum to identify anabasine and establish its presence.

Original languageEnglish
Pages (from-to)736-741
Number of pages6
JournalJournal of Forensic Sciences
Volume45
Issue number3
DOIs
StatePublished - May 2000
Externally publishedYes

Keywords

  • Fatal poisoning
  • Forensic science
  • Gas chromatography
  • Mass spectrometry (GC/MS)
  • Nicotiana glauca
  • Poisoning
  • Tobacco tree

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