Fatal Disseminated BCG Infection: An Investigation of the Immunodeficiency

Justen Passwell, David Katz, Yitzhak Frank, Zvi Spirer, Bernard E. Cohen*, Micha Ziprkowski

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

A 2-year-old boy had a fatal disseminated BCG infection. Immunologic assessment showed a normal humoral response and normal numbers of E rosettes, normal thymus weight and histological features, but an abnormal response of lymphocytes in vitro and negative skin tests. Histological examination showed the presence of Gram-negative acid-fast bacilli within the macrophages. The possible mechanisms of immunodeficiency in this patient are discussed.

Original languageEnglish
Pages (from-to)433-436
Number of pages4
JournalAmerican Journal of Diseases of Children
Volume130
Issue number4
DOIs
StatePublished - Apr 1976

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