Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis

B. Fishel; M. Tishler; D. Caspi; M. Yaron

doi:10.1136/ard.48.7.609

Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis

B. Fishel^*, M. Tishler, D. Caspi, M. Yaron

^*Corresponding author for this work

Clinical Departments

Tel Aviv Sourasky Medical Center

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment. Recovery of bone marrow was ineffective, and the patient finally died despite intensive therapeutic measures. The rare coexistence of myelotoxicity and hepatotoxicity is presented and discussed.

Original language	English
Pages (from-to)	609-610
Number of pages	2
Journal	Annals of the Rheumatic Diseases
Volume	48
Issue number	7
DOIs	https://doi.org/10.1136/ard.48.7.609
State	Published - 1989

Keywords

Hepatotoxicity
Marrow aplasia

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10.1136/ard.48.7.609

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title = "Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis",

abstract = "A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment. Recovery of bone marrow was ineffective, and the patient finally died despite intensive therapeutic measures. The rare coexistence of myelotoxicity and hepatotoxicity is presented and discussed.",

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AU - Fishel, B.

AU - Tishler, M.

AU - Caspi, D.

AU - Yaron, M.

PY - 1989

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AB - A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment. Recovery of bone marrow was ineffective, and the patient finally died despite intensive therapeutic measures. The rare coexistence of myelotoxicity and hepatotoxicity is presented and discussed.

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KW - Marrow aplasia

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JO - Annals of the Rheumatic Diseases

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Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis

Abstract

Keywords

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