Familial prolactinoma

M. Berezin; A. Karasik

doi:10.1111/j.1365-2265.1995.tb02666.x

Familial prolactinoma

M. Berezin^*
, A. Karasik

^*Corresponding author for this work

Sheba Medical Center at Tel Hashomer

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Background. Apart from the rare association with type I multiple endocrine neoplasia (MEN-1), familial types of prolactinoma have not been reported. Patients and Measurements. Eight hyperprolactinaemic patients in four families and 18 of their first and second-degree relatives (parents, children and grandchildren) were examined. Hormone levels were measured, as well as other biochemical parameters. Results. Prolactinoma was diagnosed in more than one member of each of the four families. Conclusion. Familial prolactinoma is a distinct entity which Is probably due to a genetic mutation promoting lactotroph proliferation.

Original language	English
Pages (from-to)	483-486
Number of pages	4
Journal	Clinical Endocrinology
Volume	42
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2265.1995.tb02666.x
State	Published - 1995
Externally published	Yes

Access to Document

10.1111/j.1365-2265.1995.tb02666.x

Cite this

@article{5a9452dcf4cd4f7ba27caacc037b8ba3,

title = "Familial prolactinoma",

abstract = "Background. Apart from the rare association with type I multiple endocrine neoplasia (MEN-1), familial types of prolactinoma have not been reported. Patients and Measurements. Eight hyperprolactinaemic patients in four families and 18 of their first and second-degree relatives (parents, children and grandchildren) were examined. Hormone levels were measured, as well as other biochemical parameters. Results. Prolactinoma was diagnosed in more than one member of each of the four families. Conclusion. Familial prolactinoma is a distinct entity which Is probably due to a genetic mutation promoting lactotroph proliferation.",

author = "M. Berezin and A. Karasik",

year = "1995",

doi = "10.1111/j.1365-2265.1995.tb02666.x",

language = "אנגלית",

volume = "42",

pages = "483--486",

journal = "Clinical Endocrinology",

issn = "0300-0664",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "5",

}

TY - JOUR

T1 - Familial prolactinoma

AU - Berezin, M.

AU - Karasik, A.

PY - 1995

Y1 - 1995

N2 - Background. Apart from the rare association with type I multiple endocrine neoplasia (MEN-1), familial types of prolactinoma have not been reported. Patients and Measurements. Eight hyperprolactinaemic patients in four families and 18 of their first and second-degree relatives (parents, children and grandchildren) were examined. Hormone levels were measured, as well as other biochemical parameters. Results. Prolactinoma was diagnosed in more than one member of each of the four families. Conclusion. Familial prolactinoma is a distinct entity which Is probably due to a genetic mutation promoting lactotroph proliferation.

AB - Background. Apart from the rare association with type I multiple endocrine neoplasia (MEN-1), familial types of prolactinoma have not been reported. Patients and Measurements. Eight hyperprolactinaemic patients in four families and 18 of their first and second-degree relatives (parents, children and grandchildren) were examined. Hormone levels were measured, as well as other biochemical parameters. Results. Prolactinoma was diagnosed in more than one member of each of the four families. Conclusion. Familial prolactinoma is a distinct entity which Is probably due to a genetic mutation promoting lactotroph proliferation.

UR - https://www.scopus.com/pages/publications/0028925090

U2 - 10.1111/j.1365-2265.1995.tb02666.x

DO - 10.1111/j.1365-2265.1995.tb02666.x

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 7621566

AN - SCOPUS:0028925090

SN - 0300-0664

VL - 42

SP - 483

EP - 486

JO - Clinical Endocrinology

JF - Clinical Endocrinology

IS - 5

ER -

Familial prolactinoma

Abstract

Access to Document

Other files and links

Fingerprint

Cite this