Familial prolactinoma

M. Berezin*, A. Karasik

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background. Apart from the rare association with type I multiple endocrine neoplasia (MEN-1), familial types of prolactinoma have not been reported. Patients and Measurements. Eight hyperprolactinaemic patients in four families and 18 of their first and second-degree relatives (parents, children and grandchildren) were examined. Hormone levels were measured, as well as other biochemical parameters. Results. Prolactinoma was diagnosed in more than one member of each of the four families. Conclusion. Familial prolactinoma is a distinct entity which Is probably due to a genetic mutation promoting lactotroph proliferation.

Original languageEnglish
Pages (from-to)483-486
Number of pages4
JournalClinical Endocrinology
Issue number5
StatePublished - 1995
Externally publishedYes


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