TY - JOUR
T1 - Familial prolactinoma
AU - Berezin, M.
AU - Karasik, A.
PY - 1995
Y1 - 1995
N2 - Background. Apart from the rare association with type I multiple endocrine neoplasia (MEN-1), familial types of prolactinoma have not been reported. Patients and Measurements. Eight hyperprolactinaemic patients in four families and 18 of their first and second-degree relatives (parents, children and grandchildren) were examined. Hormone levels were measured, as well as other biochemical parameters. Results. Prolactinoma was diagnosed in more than one member of each of the four families. Conclusion. Familial prolactinoma is a distinct entity which Is probably due to a genetic mutation promoting lactotroph proliferation.
AB - Background. Apart from the rare association with type I multiple endocrine neoplasia (MEN-1), familial types of prolactinoma have not been reported. Patients and Measurements. Eight hyperprolactinaemic patients in four families and 18 of their first and second-degree relatives (parents, children and grandchildren) were examined. Hormone levels were measured, as well as other biochemical parameters. Results. Prolactinoma was diagnosed in more than one member of each of the four families. Conclusion. Familial prolactinoma is a distinct entity which Is probably due to a genetic mutation promoting lactotroph proliferation.
UR - http://www.scopus.com/inward/record.url?scp=0028925090&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2265.1995.tb02666.x
DO - 10.1111/j.1365-2265.1995.tb02666.x
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C2 - 7621566
AN - SCOPUS:0028925090
SN - 0300-0664
VL - 42
SP - 483
EP - 486
JO - Clinical Endocrinology
JF - Clinical Endocrinology
IS - 5
ER -
