Familial leukopenia among Yemenite Jews

Y. Shoenfeld, A. Weinberger, R. Avishar, R. Zamir, E. Gazit, H. Joshua, J. Pinkhas

Research output: Contribution to journalArticlepeer-review


Bengin familial leukopenia was found in 75 of 200 healthy Yemenite Jews examined. The leukopenia was not a constant finding and was not associated with a tendency toward infection. HLA typing showed no significant differences in the frequency of the various HLA antigens between the subjects with and without leukopenia. No similarity was found between the HLA of the Yemenite Jews with leukopenia and that reported in black Africans with benign familial leukopenia. The suggestion of a genetic contribution from African blacks to Yemenite Jews is not supported by these results. The question remains to be answered whether the familial leukopenia in Yemenite Jews and black Africans is the result of a mutation.

Original languageEnglish
Pages (from-to)1271-1274
Number of pages4
JournalIsrael Journal of Medical Sciences
Issue number12
StatePublished - 1978
Externally publishedYes


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