Abstract
A family with genetic hypouricemia due to isolated renal tubular abnormality in urate handling is reported. Urinary urate excretion was decreased by 61% following administration of pyrazinamide, and increased by 25% following administration of probenecid. The responses to these drugs suggest genotype heterogeneity of renal hypouricemia in man.
| Original language | English |
|---|---|
| Pages (from-to) | 54-56 |
| Number of pages | 3 |
| Journal | Biomedicine Express |
| Volume | 29 |
| Issue number | 2 |
| State | Published - 1978 |