Familial hypouricemia due toisolated renal tubular abnormality

D. Benjamin, O. Sperling, A. Weinberger, J. Pinkhas

Research output: Contribution to journalArticlepeer-review

Abstract

A family with genetic hypouricemia due to isolated renal tubular abnormality in urate handling is reported. Urinary urate excretion was decreased by 61% following administration of pyrazinamide, and increased by 25% following administration of probenecid. The responses to these drugs suggest genotype heterogeneity of renal hypouricemia in man.

Original languageEnglish
Pages (from-to)54-56
Number of pages3
JournalBiomedicine Express
Volume29
Issue number2
StatePublished - 1978

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