TY - JOUR
T1 - False-positive uptake of TI-201 by an intracranial inflammatory pseudotumor
AU - Lorberboym, Mordechai
AU - Sacher, Michael
PY - 1997
Y1 - 1997
N2 - A 28-year-old man had recurrent episodes of headache, ophthalmoplegia, and ptosis. MR imaging showed a mass within the sphenoid sinus. TI-201 imaging showed intense uptake in the region of the sphenoid sinus and right middle fossa with moderate retention of activity, suggesting the diagnosis of a viable tumor. A biopsy specimen from the sphenoid sinus revealed dense inflammatory infiltrate dominated by plasma cells, consistent with inflammatory pseudotumor. After radiation therapy, the mass showed no significant change on MR imaging, but regressed in size and uptake on the follow-up TI-201 scan. TI-201 may accumulate in nonmalignant inflammatory lesions and could mimic a viable tumor. It is, therefore, suggested that before surgery and histologic diagnosis, any abnormal intracranial accumulation of TI-201 should be interpreted with caution.
AB - A 28-year-old man had recurrent episodes of headache, ophthalmoplegia, and ptosis. MR imaging showed a mass within the sphenoid sinus. TI-201 imaging showed intense uptake in the region of the sphenoid sinus and right middle fossa with moderate retention of activity, suggesting the diagnosis of a viable tumor. A biopsy specimen from the sphenoid sinus revealed dense inflammatory infiltrate dominated by plasma cells, consistent with inflammatory pseudotumor. After radiation therapy, the mass showed no significant change on MR imaging, but regressed in size and uptake on the follow-up TI-201 scan. TI-201 may accumulate in nonmalignant inflammatory lesions and could mimic a viable tumor. It is, therefore, suggested that before surgery and histologic diagnosis, any abnormal intracranial accumulation of TI-201 should be interpreted with caution.
UR - http://www.scopus.com/inward/record.url?scp=0031473561&partnerID=8YFLogxK
U2 - 10.1097/00003072-199711000-00004
DO - 10.1097/00003072-199711000-00004
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 9363383
AN - SCOPUS:0031473561
SN - 0363-9762
VL - 22
SP - 756
EP - 758
JO - Clinical Nuclear Medicine
JF - Clinical Nuclear Medicine
IS - 11
ER -