Fair localization of function via multi-lesion analysis

Alon Keinan, Alon Kaufman, Nadia Sachs, Claus C. Hilgetag, Eytan Ruppin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Acknowledging that causal localization of function in a processing network requires a multi-lesion analysis, this paper presents a rigorous and efficient method for defining and calculating the functional contributions of network elements as well as their interactions. The method's applicability to biological networks is demonstrated in the investigation of spatial attention in cats via lesion and reversible deactivation experiments.

Original languageEnglish
Pages (from-to)163-168
Number of pages6
JournalNeuroinformatics
Volume2
Issue number2
DOIs
StatePublished - 2004

Keywords

  • Contributions analysis
  • Interactions
  • Localization of function
  • Multi-lesions
  • Multi-perturbations
  • Shapley value

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