Failure or success of complex catheter-based interventional procedures assessed by intravascular ultrasound

Gad Keren, Augusto D. Pichard, Kenneth M. Kent, Lowell F. Satler, Martin B. Leon*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Intravascular ultrasound provides high resolution cross-sectional images of vessel walls and may help to characterize atherosclerotic plaque morphology subtypes. This new imaging modality may have an important role in assessing the results of standard and investigational interventional therapeutic procedures. Four case histories of patients with coronary artery disease treated with different catheter-based therapies are presented. In each case, intravascular ultrasound added diagnostic information unobtainable from standard radiographic imaging techniques. These cases, involving PTCA (balloon dilatation), directional coronary atherectomy, high-speed rotational ablation, and balloon-expandable stent implantation, each represent an interesting example of procedure success or failure that could not be fully discerned without the use of intravascular ultrasound. Specifically, the distribution of intramural dissection, the presence and magnitude of intracoronary calcification, and morphologic patterns of intimal hyperplasia leading to restenosis, were accurately identified by ultrasound images. Thus intracoronary ultrasound imaging significantly enhances the understanding of failure modes, success, and complications after therapeutic interventions in patients with complex coronary disease.

Original languageEnglish
Pages (from-to)200-208
Number of pages9
JournalAmerican Heart Journal
Issue number1
StatePublished - Jan 1992
Externally publishedYes


FundersFunder number
Netherlands Heart land Clinic International Center for Specialty National Institutes of Health


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