Failure of sentinel node identification following neo-adjuvant chemo-radiotherapy for locally advanced squamous cell carcinoma of the vulva

H. Levavi*, G. Sabah, R. Hardoff, C. Koren, H. Gutman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A case of a 70-year-old patient with advanced local vulvar cancer is presented. Treatment with neo-adjuvant chemo-radiotherapy for two courses was administered and two weeks after completion of treatment the patient underwent wide local excision with bilateral inguino-femoral lymph node dissection through three separate incisions. Two methods for the evaluation of sentinel nodes-lymphoscintigraphy and intraoperative gamma hand-held probe and blue dye injection, did not detect any sentinel node on either side. Groin-node dissection revealed 23 negative nodes. It is our hypothesis that the non-visualization of sentinel nodes in this patient was due to post-irradiation damage to the lymph channels.

Original languageEnglish
Pages (from-to)433-434
Number of pages2
JournalEuropean Journal of Gynaecological Oncology
Volume24
Issue number5
StatePublished - 2003
Externally publishedYes

Keywords

  • Lymphoscintigraphy
  • Sentinel node
  • Vulvar cancer

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