TY - JOUR
T1 - Failure of quality control measures to prevent reporting of false resistance to imipenem, resulting in a pseudo-outbreak of imipenem-resistant Pseudomonas aeruginosa
AU - Carmeli, Yehuda
AU - Eichelberger, Karen
AU - Soja, Don
AU - Dakos, Joanna
AU - Venkataraman, Lata
AU - DeGirolami, Paola
AU - Samore, Matthew
PY - 1998/2
Y1 - 1998/2
N2 - False results showing an outbreak of Pseudomonas aeruginosa with resistance to imipenem were traced to a defective lot of microdilution MIC testing panels. These panels contained two- to threefold lower concentrations of imipenem than expected and resulted in artifactual two- to fourfold increases in MICs of imipenem. The quality-control MIC results for Pseudomonas aeruginosa ATCC 27853 were 4 μg/ml, the highest value within the range recommended by the National Committee for Clinical Laboratory Standards. We recommend that this value be considered out of the quality- control range.
AB - False results showing an outbreak of Pseudomonas aeruginosa with resistance to imipenem were traced to a defective lot of microdilution MIC testing panels. These panels contained two- to threefold lower concentrations of imipenem than expected and resulted in artifactual two- to fourfold increases in MICs of imipenem. The quality-control MIC results for Pseudomonas aeruginosa ATCC 27853 were 4 μg/ml, the highest value within the range recommended by the National Committee for Clinical Laboratory Standards. We recommend that this value be considered out of the quality- control range.
UR - http://www.scopus.com/inward/record.url?scp=0031965582&partnerID=8YFLogxK
U2 - 10.1128/jcm.36.2.595-597.1998
DO - 10.1128/jcm.36.2.595-597.1998
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C2 - 9466787
AN - SCOPUS:0031965582
VL - 36
SP - 595
EP - 597
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 2
ER -