Extensive review based on a rare case of histiocytic sarcoma

Milena Tocut*, Hanan Vaknine, Paulina Potachenko, Sorin Elias, Gisele Zandman-Goddard

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Histiocytic sarcoma is a rare hematopoietic malignancy originating from the monocyte/macrophage bone marrow lineage. HS can occur in isolation or in association with other hemato-logical neoplasms such as non-Hodgkin's lymphoma, myelo-dysplasia, or acute leukemia. Clinically, HS can affect lymph nodes, gastrointestinal tract, skin, bone marrow, and spleen as well as the central nervous system. Most cases of HS follow an aggressive clinical course, with most patients dying of progressive disease within one year of diagnosis.

Original languageEnglish
Pages (from-to)579-581
Number of pages3
JournalIsrael Medical Association Journal
Issue number10
StatePublished - Oct 2020


  • Bad prognosis
  • Bone marrow
  • Histiocytic sarcoma
  • Immuno-histochemistry
  • Lymphadenopathy


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