Abstract
An antigen immunologically cross-reacting with the murine mammary virus major glycoprotein (gp52) was found on the cell surfaces of a human breast cancer cell line (T-47D) and its subcloned derivatives. The presence of this antigen was established by various immunological methods: indirect immunoperoxidase technique on live and fixed cells, indirect radioimmunoassay of live cells and immunoscanning electron microscopy. We therefore propose the T-47D cell line and its subclones as an in vitro model system for studying the modulation of expression of this tumor-associated antigen.
Original language | English |
---|---|
Pages (from-to) | 37-44 |
Number of pages | 8 |
Journal | Cancer Letters |
Volume | 17 |
Issue number | 1 |
DOIs | |
State | Published - Oct 1982 |