Experimental models of Behçet's disease

Ehud Baharav, Abraham Weinberger, Felix Mor*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Behçet's disease (BD) is a chronic systemic inflammatory disease of unknown etiology. Its prevalence has a unique geographic distribution from the Far East to the Mediterranean basin. In addition, the majority of patients carry the class I HLA-B51 gene as a genetic marker. Therefore, the proposed etiological factors might be environmental, infectious, genetic, autoimmune and a combination thereof. A crucial review of the current experimental animal models for BD and their relevance to the human disease are presented.

Original languageEnglish
Pages (from-to)11-14
Number of pages4
JournalDrug Discovery Today: Disease Models
Issue number1
StatePublished - 2006
Externally publishedYes


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