TY - JOUR
T1 - Experimental models of Behçet's disease
AU - Baharav, Ehud
AU - Weinberger, Abraham
AU - Mor, Felix
PY - 2006
Y1 - 2006
N2 - Behçet's disease (BD) is a chronic systemic inflammatory disease of unknown etiology. Its prevalence has a unique geographic distribution from the Far East to the Mediterranean basin. In addition, the majority of patients carry the class I HLA-B51 gene as a genetic marker. Therefore, the proposed etiological factors might be environmental, infectious, genetic, autoimmune and a combination thereof. A crucial review of the current experimental animal models for BD and their relevance to the human disease are presented.
AB - Behçet's disease (BD) is a chronic systemic inflammatory disease of unknown etiology. Its prevalence has a unique geographic distribution from the Far East to the Mediterranean basin. In addition, the majority of patients carry the class I HLA-B51 gene as a genetic marker. Therefore, the proposed etiological factors might be environmental, infectious, genetic, autoimmune and a combination thereof. A crucial review of the current experimental animal models for BD and their relevance to the human disease are presented.
UR - http://www.scopus.com/inward/record.url?scp=33646491019&partnerID=8YFLogxK
U2 - 10.1016/j.ddmod.2006.03.008
DO - 10.1016/j.ddmod.2006.03.008
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AN - SCOPUS:33646491019
SN - 1740-6757
VL - 3
SP - 11
EP - 14
JO - Drug Discovery Today: Disease Models
JF - Drug Discovery Today: Disease Models
IS - 1
ER -
