Experimental models in focal cerebral ischemia: Are we there yet?

R. R. Leker*, S. Constantini

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Therapeutic options available for acute stroke management are sparse and inadequate. Therefore, new insights into stroke pathophysiology leading to new therapeutic targets are needed. In order to attain these goals, adequate animal models for cerebral ischemia are needed. In the following paper the authors will review the various animal models for stroke and emphasize their potential strengths and weaknesses.

Original languageEnglish
Pages (from-to)55-59
Number of pages5
JournalActa Neurochirurgica, Supplement
Issue number83
StatePublished - 2002


  • Animal
  • Cerebral ischemia
  • Experimental models
  • Stroke


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