Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma

Maroulio Pertesi; Maxime Vallée; Xiaomu Wei; Maria V. Revuelta; Perrine Galia; Delphine Demangel; Javier Oliver; Matthieu Foll; Siwei Chen; Emeline Perrial; Laurent Garderet; Jill Corre; Xavier Leleu; Eileen M. Boyle; Olivier Decaux; Philippe Rodon; Brigitte Kolb; Borhane Slama; Philippe Mineur; Eric Voog; Catherine Le Bris; Jean Fontan; Michel Maigre; Marie Beaumont; Isabelle Azais; Hagay Sobol; Marguerite Vignon; Bruno Royer; Aurore Perrot; Jean Gabriel Fuzibet; Véronique Dorvaux; Bruno Anglaret; Pascale Cony-Makhoul; Christian Berthou; Florence Desquesnes; Brigitte Pegourie; Serge Leyvraz; Laurent Mosser; Nicole Frenkiel; Karine Augeul-Meunier; Isabelle Leduc; Cécile Leyronnas; Laurent Voillat; Philippe Casassus; Claire Mathiot; Nathalie Cheron; Etienne Paubelle; Philippe Moreau; Yves–Jean –J Bignon; Bertrand Joly; Pascal Bourquard; Denis Caillot; Hervé Naman; Sophie Rigaudeau; Gérald Marit; Margaret Macro; Isabelle Lambrecht; Manuel Cliquennois; Laure Vincent; Philippe Helias; Hervé Avet-Loiseau; Victor Moreno; Rui Manuel Reis; Judit Varkonyi; Marcin Kruszewski; Annette Juul Vangsted; Artur Jurczyszyn; Jan Maciej Zaucha; Juan Sainz; Malgorzata Krawczyk-Kulis; Marzena Wątek; Matteo Pelosini; Elzbieta Iskierka-Jażdżewska; Norbert Grząśko; Joaquin Martinez-Lopez; Andrés Jerez; Daniele Campa; Gabriele Buda; Fabienne Lesueur; Marek Dudziński; Ramón García-Sanz; Arnon Nagler; Marcin Rymko; Krzysztof Jamroziak; Aleksandra Butrym; Federico Canzian; Ofure Obazee; Björn Nilsson; Robert J. Klein; Steven M. Lipkin; James D. McKay; Charles Dumontet

doi:10.1038/s41375-019-0452-6

Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma

Maroulio Pertesi, Maxime Vallée, Xiaomu Wei, Maria V. Revuelta, Perrine Galia, Delphine Demangel, Javier Oliver, Matthieu Foll, Siwei Chen, Emeline Perrial, Laurent Garderet, Jill Corre, Xavier Leleu, Eileen M. Boyle, Olivier Decaux, Philippe Rodon, Brigitte Kolb, Borhane Slama, Philippe Mineur, Eric VoogCatherine Le Bris, Jean Fontan, Michel Maigre, Marie Beaumont, Isabelle Azais, Hagay Sobol, Marguerite Vignon, Bruno Royer, Aurore Perrot, Jean Gabriel Fuzibet, Véronique Dorvaux, Bruno Anglaret, Pascale Cony-Makhoul, Christian Berthou, Florence Desquesnes, Brigitte Pegourie, Serge Leyvraz, Laurent Mosser, Nicole Frenkiel, Karine Augeul-Meunier, Isabelle Leduc, Cécile Leyronnas, Laurent Voillat, Philippe Casassus, Claire Mathiot, Nathalie Cheron, Etienne Paubelle, Philippe Moreau, Yves–Jean –J Bignon, Bertrand Joly, Pascal Bourquard, Denis Caillot, Hervé Naman, Sophie Rigaudeau, Gérald Marit, Margaret Macro, Isabelle Lambrecht, Manuel Cliquennois, Laure Vincent, Philippe Helias, Hervé Avet-Loiseau, Victor Moreno, Rui Manuel Reis, Judit Varkonyi, Marcin Kruszewski, Annette Juul Vangsted, Artur Jurczyszyn, Jan Maciej Zaucha, Juan Sainz, Malgorzata Krawczyk-Kulis, Marzena Wątek, Matteo Pelosini, Elzbieta Iskierka-Jażdżewska, Norbert Grząśko, Joaquin Martinez-Lopez, Andrés Jerez, Daniele Campa, Gabriele Buda, Fabienne Lesueur, Marek Dudziński, Ramón García-Sanz, Arnon Nagler, Marcin Rymko, Krzysztof Jamroziak, Aleksandra Butrym, Federico Canzian, Ofure Obazee, Björn Nilsson, Robert J. Klein, Steven M. Lipkin, James D. McKay^*, Charles Dumontet

^*Corresponding author for this work

Research output: Contribution to journal › Letter › peer-review

34 Scopus citations

Original language	English
Pages (from-to)	2324-2330
Number of pages	7
Journal	Leukemia
Volume	33
Issue number	9
DOIs	https://doi.org/10.1038/s41375-019-0452-6
State	Published - 1 Sep 2019
Externally published	Yes

Funding

Funders	Funder number
FFMRG
Fondation Française pour la Recherche contre le Myélome et les Gammapathies
Intergroupe Francophone du Myélome	R01 NCI CA167824
National Institutes of Health	S10OD018522
National Cancer Institute	R01CA167824
Center for Strategic Scientific Initiatives, National Cancer Institute
Institut National du Cancer

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10.1038/s41375-019-0452-6

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Pertesi, M., Vallée, M., Wei, X., Revuelta, M. V., Galia, P., Demangel, D., Oliver, J., Foll, M., Chen, S., Perrial, E., Garderet, L., Corre, J., Leleu, X., Boyle, E. M., Decaux, O., Rodon, P., Kolb, B., Slama, B., Mineur, P., ... Dumontet, C. (2019). Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma. Leukemia, 33(9), 2324-2330. https://doi.org/10.1038/s41375-019-0452-6

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title = "Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma",

author = "Maroulio Pertesi and Maxime Vall{\'e}e and Xiaomu Wei and Revuelta, {Maria V.} and Perrine Galia and Delphine Demangel and Javier Oliver and Matthieu Foll and Siwei Chen and Emeline Perrial and Laurent Garderet and Jill Corre and Xavier Leleu and Boyle, {Eileen M.} and Olivier Decaux and Philippe Rodon and Brigitte Kolb and Borhane Slama and Philippe Mineur and Eric Voog and {Le Bris}, Catherine and Jean Fontan and Michel Maigre and Marie Beaumont and Isabelle Azais and Hagay Sobol and Marguerite Vignon and Bruno Royer and Aurore Perrot and Fuzibet, {Jean Gabriel} and V{\'e}ronique Dorvaux and Bruno Anglaret and Pascale Cony-Makhoul and Christian Berthou and Florence Desquesnes and Brigitte Pegourie and Serge Leyvraz and Laurent Mosser and Nicole Frenkiel and Karine Augeul-Meunier and Isabelle Leduc and C{\'e}cile Leyronnas and Laurent Voillat and Philippe Casassus and Claire Mathiot and Nathalie Cheron and Etienne Paubelle and Philippe Moreau and Bignon, {Yves–Jean –J} and Bertrand Joly and Pascal Bourquard and Denis Caillot and Herv{\'e} Naman and Sophie Rigaudeau and G{\'e}rald Marit and Margaret Macro and Isabelle Lambrecht and Manuel Cliquennois and Laure Vincent and Philippe Helias and Herv{\'e} Avet-Loiseau and Victor Moreno and Reis, {Rui Manuel} and Judit Varkonyi and Marcin Kruszewski and Vangsted, {Annette Juul} and Artur Jurczyszyn and Zaucha, {Jan Maciej} and Juan Sainz and Malgorzata Krawczyk-Kulis and Marzena W{\c a}tek and Matteo Pelosini and Elzbieta Iskierka-Ja{\.z}d{\.z}ewska and Norbert Grz{\c a}{\'s}ko and Joaquin Martinez-Lopez and Andr{\'e}s Jerez and Daniele Campa and Gabriele Buda and Fabienne Lesueur and Marek Dudzi{\'n}ski and Ram{\'o}n Garc{\'i}a-Sanz and Arnon Nagler and Marcin Rymko and Krzysztof Jamroziak and Aleksandra Butrym and Federico Canzian and Ofure Obazee and Bj{\"o}rn Nilsson and Klein, {Robert J.} and Lipkin, {Steven M.} and McKay, {James D.} and Charles Dumontet",

note = "Funding Information: Acknowledgements This work was supported by the French National Cancer Institute (INCA) and the Fondation Fran{\c c}aise pour la Recherche contre le My{\'e}lome et les Gammapathies (FFMRG), the Intergroupe Francophone du My{\'e}lome (IFM), NCI R01 NCI CA167824 and a generous donation from Matthew Bell. This work was supported in part through the computational resources and staff expertise provided by Scientific Computing at the Icahn School of Medicine at Mount Sinai. Research reported in this paper was supported by the Office of Research Infrastructure of the National Institutes of Health under award number S10OD018522. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors thank the Association des Malades du My{\'e}lome Multiple (AF3M) for their continued support and participation. Where authors are identified as personnel of the International Agency for Research on Cancer / World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy or views of the International Agency for Research on Cancer / World Health Organization.",

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volume = "33",

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Pertesi, M, Vallée, M, Wei, X, Revuelta, MV, Galia, P, Demangel, D, Oliver, J, Foll, M, Chen, S, Perrial, E, Garderet, L, Corre, J, Leleu, X, Boyle, EM, Decaux, O, Rodon, P, Kolb, B, Slama, B, Mineur, P, Voog, E, Le Bris, C, Fontan, J, Maigre, M, Beaumont, M, Azais, I, Sobol, H, Vignon, M, Royer, B, Perrot, A, Fuzibet, JG, Dorvaux, V, Anglaret, B, Cony-Makhoul, P, Berthou, C, Desquesnes, F, Pegourie, B, Leyvraz, S, Mosser, L, Frenkiel, N, Augeul-Meunier, K, Leduc, I, Leyronnas, C, Voillat, L, Casassus, P, Mathiot, C, Cheron, N, Paubelle, E, Moreau, P, Bignon, YJJ, Joly, B, Bourquard, P, Caillot, D, Naman, H, Rigaudeau, S, Marit, G, Macro, M, Lambrecht, I, Cliquennois, M, Vincent, L, Helias, P, Avet-Loiseau, H, Moreno, V, Reis, RM, Varkonyi, J, Kruszewski, M, Vangsted, AJ, Jurczyszyn, A, Zaucha, JM, Sainz, J, Krawczyk-Kulis, M, Wątek, M, Pelosini, M, Iskierka-Jażdżewska, E, Grząśko, N, Martinez-Lopez, J, Jerez, A, Campa, D, Buda, G, Lesueur, F, Dudziński, M, García-Sanz, R, Nagler, A, Rymko, M, Jamroziak, K, Butrym, A, Canzian, F, Obazee, O, Nilsson, B, Klein, RJ, Lipkin, SM, McKay, JD & Dumontet, C 2019, 'Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma', Leukemia, vol. 33, no. 9, pp. 2324-2330. https://doi.org/10.1038/s41375-019-0452-6

TY - JOUR

T1 - Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma

AU - Pertesi, Maroulio

AU - Vallée, Maxime

AU - Wei, Xiaomu

AU - Revuelta, Maria V.

AU - Galia, Perrine

AU - Demangel, Delphine

AU - Oliver, Javier

AU - Foll, Matthieu

AU - Chen, Siwei

AU - Perrial, Emeline

AU - Garderet, Laurent

AU - Corre, Jill

AU - Leleu, Xavier

AU - Boyle, Eileen M.

AU - Decaux, Olivier

AU - Rodon, Philippe

AU - Kolb, Brigitte

AU - Slama, Borhane

AU - Mineur, Philippe

AU - Voog, Eric

AU - Le Bris, Catherine

AU - Fontan, Jean

AU - Maigre, Michel

AU - Beaumont, Marie

AU - Azais, Isabelle

AU - Sobol, Hagay

AU - Vignon, Marguerite

AU - Royer, Bruno

AU - Perrot, Aurore

AU - Fuzibet, Jean Gabriel

AU - Dorvaux, Véronique

AU - Anglaret, Bruno

AU - Cony-Makhoul, Pascale

AU - Berthou, Christian

AU - Desquesnes, Florence

AU - Pegourie, Brigitte

AU - Leyvraz, Serge

AU - Mosser, Laurent

AU - Frenkiel, Nicole

AU - Augeul-Meunier, Karine

AU - Leduc, Isabelle

AU - Leyronnas, Cécile

AU - Voillat, Laurent

AU - Casassus, Philippe

AU - Mathiot, Claire

AU - Cheron, Nathalie

AU - Paubelle, Etienne

AU - Moreau, Philippe

AU - Bignon, Yves–Jean –J

AU - Joly, Bertrand

AU - Bourquard, Pascal

AU - Caillot, Denis

AU - Naman, Hervé

AU - Rigaudeau, Sophie

AU - Marit, Gérald

AU - Macro, Margaret

AU - Lambrecht, Isabelle

AU - Cliquennois, Manuel

AU - Vincent, Laure

AU - Helias, Philippe

AU - Avet-Loiseau, Hervé

AU - Moreno, Victor

AU - Reis, Rui Manuel

AU - Varkonyi, Judit

AU - Kruszewski, Marcin

AU - Vangsted, Annette Juul

AU - Jurczyszyn, Artur

AU - Zaucha, Jan Maciej

AU - Sainz, Juan

AU - Krawczyk-Kulis, Malgorzata

AU - Wątek, Marzena

AU - Pelosini, Matteo

AU - Iskierka-Jażdżewska, Elzbieta

AU - Grząśko, Norbert

AU - Martinez-Lopez, Joaquin

AU - Jerez, Andrés

AU - Campa, Daniele

AU - Buda, Gabriele

AU - Lesueur, Fabienne

AU - Dudziński, Marek

AU - García-Sanz, Ramón

AU - Nagler, Arnon

AU - Rymko, Marcin

AU - Jamroziak, Krzysztof

AU - Butrym, Aleksandra

AU - Canzian, Federico

AU - Obazee, Ofure

AU - Nilsson, Björn

AU - Klein, Robert J.

AU - Lipkin, Steven M.

AU - McKay, James D.

AU - Dumontet, Charles

N1 - Funding Information: Acknowledgements This work was supported by the French National Cancer Institute (INCA) and the Fondation Française pour la Recherche contre le Myélome et les Gammapathies (FFMRG), the Intergroupe Francophone du Myélome (IFM), NCI R01 NCI CA167824 and a generous donation from Matthew Bell. This work was supported in part through the computational resources and staff expertise provided by Scientific Computing at the Icahn School of Medicine at Mount Sinai. Research reported in this paper was supported by the Office of Research Infrastructure of the National Institutes of Health under award number S10OD018522. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors thank the Association des Malades du Myélome Multiple (AF3M) for their continued support and participation. Where authors are identified as personnel of the International Agency for Research on Cancer / World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy or views of the International Agency for Research on Cancer / World Health Organization.

PY - 2019/9/1

Y1 - 2019/9/1

UR - http://www.scopus.com/inward/record.url?scp=85064218541&partnerID=8YFLogxK

U2 - 10.1038/s41375-019-0452-6

DO - 10.1038/s41375-019-0452-6

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C2 - 30967618

AN - SCOPUS:85064218541

SN - 0887-6924

VL - 33

SP - 2324

EP - 2330

JO - Leukemia

JF - Leukemia

IS - 9

ER -

Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma

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