Exertional rhabdomyolysis

Eran Keltz, Fahmi Yousef Khan, Gideon Mann

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Rhabdomyolysis syndrome has many acquired pathophysiological causes, resulting in a common pathway of muscle tissue degradation and the dispersing of its components onto circulation, causing systemic effects such as electrolyte abnormalities, arrhythmia, kidney injury, compartment syndrome, and DIC. Exertional rhabdomyolysis (ER) is the most common cause among young persons. It is related to several risk factors such as temperature extremes, humidity, dehydration, fatigue, asthma, HMG-CoA reductase inhibitors (statins) consumption, and congenital defects such as sickle-cell trait and myopathy. Although usually ER has a rather benign course, complications should be anticipated and referred, and a high index of suspicion is recommended. Guidelines for diagnosis and management are provided.

Original languageEnglish
Title of host publicationSports Injuries
Subtitle of host publicationPrevention, Diagnosis, Treatment and Rehabilitation, Second Edition
PublisherSpringer Berlin Heidelberg
Number of pages16
ISBN (Electronic)9783642365690
ISBN (Print)9783642365683
StatePublished - 1 Jan 2015


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