Exacerbation of pulmonary sarcoidosis after liver transplantation

Oren Shibolet, Yossi Kalish, Dana Wolf, Orit Pappo, Uri Laxer, Neville Berkman, Dorit Shaham, Yaffa Ashur, Yaron Ilan

Research output: Contribution to journalArticlepeer-review

Abstract

Patients with hepatic sarcoidosis rarely require orthotopic liver transplantation (OLT). Progression of granulomatous activity involving other organs after OLT has rarely been described. We describe a 32-year-old woman who underwent liver transplantation for sarcoidosis-associated end-stage liver disease. She presented 4 years later with shortness of breath, hilar lymphadenopathy, and interstitial lung abnormalities. Liver functions were normal. Open lung biopsy results revealed granulomata compatible with sarcoidosis. The patient made a complete recovery after corticosteroid treatment. To the best of our knowledge, this is a first description of severe exacerbation of pulmonary sarcoidosis in an immunosuppressed patient who underwent liver transplantation for sarcoidosis-associated liver disease.

Original languageEnglish
Pages (from-to)356-358
Number of pages3
JournalJournal of Clinical Gastroenterology
Volume35
Issue number4
DOIs
StatePublished - Oct 2002
Externally publishedYes

Keywords

  • Liver transplantation
  • Sarcoidosis

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