Evolution of reduced mutation under frequency-dependent selection

Uri Liberman, Hilla Behar, Marcus W. Feldman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Most models for the evolution of mutation under frequency-dependent selection involve some form of host–parasite interaction. These generally involve cyclic dynamics under which mutation may increase. Here we show that the reduction principle for the evolution of mutation, which is generally true for frequency-independent selection, also holds under frequency-dependent selection on haploids and diploids that does not involve cyclic dynamics.

Original languageEnglish
Pages (from-to)52-59
Number of pages8
JournalTheoretical Population Biology
StatePublished - 1 Dec 2016


FundersFunder number
Stanford University


    • Diploid model
    • Frequency dependence
    • Multiple modifier alleles
    • Reduction principle


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