Evolution of palmar skin creases in the Ehlers‐Danlos syndrome

R. M. Goodman*, M. Bat‐Miriam Katznelson, M. Frydman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The Ehlers‐Danlos syndrome (E‐D) is a well recognized genetic disorder of connective tissue of unknown etiology. In the classical form of the disease, skin and joint changes involving the hand often suggest the clinical diagnosis. By studying three affected members in three generations of a family with E‐D by means of fingerprint analysis, we have shown the evolution of secondary palmar creases. The possible etiology and significance of these secondary skin creases are discussed.

Original languageEnglish
Pages (from-to)67-72
Number of pages6
JournalClinical Genetics
Issue number1
StatePublished - Jan 1972


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