TY - JOUR
T1 - Evolution of isopenicillin N synthase genes may have involved horizontal gene transfer
AU - Landan, Giddy
AU - Cohen, Gerald
AU - Aharonowitz, Yair
AU - Shuali, Yuval
AU - Graur, Dan
AU - Shiffman, Dov
PY - 1990
Y1 - 1990
N2 - The isopenicillin N synthase genes from three fungal species, three Gram-positive species, and one Gram-negative bacterial species share an unusually high sequence similarity. A phylogentic analysis was earned out to determine which type of evolutionary scenario best accounts for this similarity. The most plausible scenario is one in which a horizontal gene-transfer event, from the prokaryotes to the eukaryotes. occurred at a time close to the divergence between the Gram-positive and the Gram-negative bacteria.
AB - The isopenicillin N synthase genes from three fungal species, three Gram-positive species, and one Gram-negative bacterial species share an unusually high sequence similarity. A phylogentic analysis was earned out to determine which type of evolutionary scenario best accounts for this similarity. The most plausible scenario is one in which a horizontal gene-transfer event, from the prokaryotes to the eukaryotes. occurred at a time close to the divergence between the Gram-positive and the Gram-negative bacteria.
KW - Horizontal gene transfer
KW - Isopenicillin n synthase
UR - http://www.scopus.com/inward/record.url?scp=0025128056&partnerID=8YFLogxK
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AN - SCOPUS:0025128056
SN - 0737-4038
VL - 7
SP - 399
EP - 406
JO - Molecular Biology and Evolution
JF - Molecular Biology and Evolution
IS - 5
ER -