TY - JOUR
T1 - Evidence-based medicine in the treatment of peritoneal carcinomatosis
T2 - Past, present, and future
AU - Nissan, Aviram
AU - Stojadinovic, Alexander
AU - Garofalo, Alfredo
AU - Esquivel, Jesus
AU - Piso, Pompiliu
PY - 2009/9/15
Y1 - 2009/9/15
N2 - The current treatment of peritoneal surface malignancies (PSMs) is moving from a nihilistic approach, into a combined modality approach offering selected patients long-term survival. As primary PSM are rare, extrapolation of data from clinical trials of related disease is necessary to develop treatment guidelines. Secondary PSM are more common, and therefore, treatment guidelines should be developed based on prospective clinical trials. We reviewed the published and ongoing clinical trials studying the treatment of PSM.
AB - The current treatment of peritoneal surface malignancies (PSMs) is moving from a nihilistic approach, into a combined modality approach offering selected patients long-term survival. As primary PSM are rare, extrapolation of data from clinical trials of related disease is necessary to develop treatment guidelines. Secondary PSM are more common, and therefore, treatment guidelines should be developed based on prospective clinical trials. We reviewed the published and ongoing clinical trials studying the treatment of PSM.
KW - Carcinomatosis
KW - Clinical trial
KW - Cytoreduction
KW - Hyperthermic chemotherapy
KW - Peritoneal surface malignancies
UR - http://www.scopus.com/inward/record.url?scp=69749097864&partnerID=8YFLogxK
U2 - 10.1002/jso.21323
DO - 10.1002/jso.21323
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C2 - 19697442
AN - SCOPUS:69749097864
SN - 0022-4790
VL - 100
SP - 335
EP - 344
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 4
ER -