Evaluation of the Hachinski ischemic scale in a prospective study

M. Nussbaum, T. A. Treves, A. D. Korczyn*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The Hachinski ischemic scale (HIS) is the favored clinical tool used in the differentiation between degenerative dementia and multi-infarct dementia. Application of the HIS results in an additional subtype of dementia termed 'mixed' dementia. More significantly, distribution of the scores obtained has a skewed rather than a bimodal pattern, which does not agree with the original framework of the test, namely to distinguish between the two different nosological entities. This prompted us to evaluate the scale, and a modification is proposed in which several non-discriminating items are excluded. Application of the modified HIS to a series of 98 demented patients consecutively admitted to a drug study, resulted in a bimodal distribution of the scores obtained and in a smaller size of the intermediate group, supporting the improved diagnostic reliability of this version.

Original languageEnglish
Pages (from-to)10-14
Number of pages5
Issue number1
StatePublished - 1992


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