Evaluation of adrenocortical carcinoma in an infant using Ga-67 scintigraphy

An infant with adrenocortical carcinoma revealed by Ga-67 scintigraphy is described. Adrenocortical carcinoma is a rare neoplasm, with an annual prevalence of two new cases per million population. An English literature search revealed only a few cases detected by Ga-67, with only one child described. Most children with adrenocortical carcinoma have functional tumors, so clinical presentation consists of virilizing signs in girls and pseudo-precocious puberty in boys, Cushing syndrome, accelerated growth, advanced bone age, and hypertension. Diagnosis is established by different imaging methods, combined with elevated serum adrenal steroid levels. Complete surgical resection is the preferred treatment.