Evaluating treatments for preterm labor: possible solutions for some methodological problems

Haim Omer*, Zvi Palti, Dov Friedlander

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The usual evaluation procedures for labor-inhibiting therapies are criticized and a new measure is proposed. This measure (rate of pregnancy prolongation) is shown to fulfil the criteria of high sensitivity to treatment effects and of unbiasedness for the gestational age of patients. The use of analysis of covariance is proposed as a solution for the problem of confounding background variables. The advantages of the new evaluation procedure are illustrated by the analysis of a clinical trial of labor inhibition by hypnotic relaxation.

Original languageEnglish
Pages (from-to)229-236
Number of pages8
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume22
Issue number4
DOIs
StatePublished - Aug 1986
Externally publishedYes

Keywords

  • analysis of covariance
  • evaluation of treatments
  • preterm labor

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