EULAR recommendations for the management and vaccination of people with rheumatic and musculoskeletal diseases in the context of SARSCoV-2: the November 2021 update

Robert B.M. Landewé*, Féline P.B. Kroon, Alessia Alunno, Aurélie Najm, Johannes W.J. Bijlsma, Gerd Rüdiger R. Burmester, Roberto Caporali, Bernard Combe, Richard Conway, Jeffrey R. Curtis, Ori Elkayam, Laure Gossec, Marloes W. Heijstek, Lukas Haupt, Annamaria Iagnocco, John D. Isaacs, István Ábel Juhász, Suzi Makri, Xavier Mariette, Iain B. McInnesPuja Mehta, Ulf Mueller-Ladner, Hendrik Schulze-Koops, Josef S. Smolen, Dieter Wiek, Kevin L. Winthrop, Victoria Navarro-Compán, Pedro M. Machado

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

120 Scopus citations

Abstract

The first EULAR provisional recommendations on the management of rheumatic and musculoskeletal diseases (RMDs) in the context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), largely based on expert opinion, were published in June 2020. Since then, an unprecedented number of clinical studies have accrued in the literature. Several SARS-CoV-2 vaccines have been approved for population-wide vaccination programmes in EULAR-affiliated countries. Studies regarding vaccination of patients with (inflammatory) RMDs have released their first results or are underway. EULAR found it opportune to carefully review to what extent the initially consensus expert recommendations stood the test of time, by challenging them with the recently accumulated body of scientific evidence, and by incorporating evidence-based advice on SARS-CoV-2 vaccination. EULAR started a formal (first) update in January 2021, performed a systematic literature review according to EULAR’s standard operating procedures and completed a set of updated overarching principles and recommendations in July 2021. Two points to consider were added in November 2021, because of recent developments pertaining to additional vaccination doses.

Original languageEnglish
Pages (from-to)1628-1639
Number of pages12
JournalAnnals of the Rheumatic Diseases
Volume81
Issue number12
DOIs
StatePublished - 2022
Externally publishedYes

Funding

FundersFunder number
NIHR Newcastle Biomedical Research Centre in Ageing and Long-term Conditions
NIHR University College London Hospitals
National Health Service
Research Into Inflammatory Arthritis Centre Versus Arthritis
National Institute for Health and Care Research
Department of Health and Social Care
University College London Hospitals NHS Foundation Trust
UCLH Biomedical Research Centre

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