Etretinate‐induced skeletal muscle damage

EMMILIA HODAK*, M. DAVID, N. GADOTH, MIRIAM SANDBANK

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Three patients who received etretinate, two for psoriasis vulgaris and one for exfoliative dermatitis, developed clinical and electromyographic features of muscle damage during treatment. In one patient histological and ultrastructural findings indicated segmental muscle necrosis. Withdrawal of the drug led to clinical recovery and normalization of muscle enzyme levels and electromyogram. To the best of our knowledge, this is the first report to show etretinate‐induced reversible skeletal muscle damage.

Original languageEnglish
Pages (from-to)623-626
Number of pages4
JournalBritish Journal of Dermatology
Volume116
Issue number5
DOIs
StatePublished - May 1987

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