Ethnic differences among implantable cardioverter defibrillators recipients in Israel

Avi Sabbag, Mahmoud Suleiman, Aharon Glick, Aharon Medina, Gregory Golovchiner, Hillel Steiner, Michael Arad, Ilan Goldenberg, Michael Glikson, Roy Beinart*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Heart failure is an increasingly common condition arising from a variety of different pathophysiological processes. Little is known about the unique features of Israeli Arabs who present with heart failure and who undergo cardiac device implantation. The study population comprised of 4,671 patients who were enrolled in the national Israeli Implantable Cardioverter Defibrillator registry. We compared demographic, clinical, and echocardiographic characteristics; device-related indications; and outcomes between Israeli Arabs (n = 733) and Jews (n = 3,938), who were enrolled in the registry from July 2010 through December 2013. Israeli Arabs constituted 15.7% of the study population. They were younger at presentation compared with Jews (57 ± 15 vs 66 ± 12 years, respectively; p <0.001), with a greater burden of co-morbidities, including diabetes mellitus and chronic obstructive lung disease and smoking. In addition, Arab patients had a greater frequency of non-ischemic cardiomyopathy (40.2% vs 24.6%, respectively; p <0.001), which was associated with a greater frequency of familial history of sudden cardiac death. During 15 ± 9 month follow-up, the mortality rates and appropriate device therapy were similar in both ethnic groups. In conclusion, Israeli Arab patients implanted with implantable cardioverter defibrillators display unique clinical features with greater prevalence of non-ischemic cardiomyopathy characterized by an early-onset and rapid deterioration.

Original languageEnglish
Pages (from-to)1102-1106
Number of pages5
JournalAmerican Journal of Cardiology
Volume115
Issue number8
DOIs
StatePublished - 2015

Funding

FundersFunder number
Israeli Heart Society
Boston Scientific CorporationISROTH20063, ISROTH20184
Israeli Association for Cardiovascular Trials

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