Estimation of coronary stenosis severity based on flow distribution ratios

Idit Avrahami*, Hadar Biran, Alexander Liberzon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We suggest improving minimally-invasive stenosis severity estimation, using a combination of existing geometry-based methods with Transluminal Attenuation Gradient measurements. Instead of local flow values, the method uses flow distribution ratios along the entire tree. The tree geometry is used to derive a lumped model and predict the ‘theoretical’ ratios in each bifurcation, while attenuation measurements are used for extracting ‘actual’ ratios. The discrepancies between the measured and the theoretical values are utilized to assess a functional degree of stenosis. Our experimental and numerical analyses show that the quantitative value of discrepancy is proportional to stenosis severity, regardless of boundary conditions.

Original languageEnglish
Pages (from-to)424-438
Number of pages15
JournalComputer Methods in Biomechanics and Biomedical Engineering
Issue number4
StatePublished - 2022


FundersFunder number
Tel Aviv University
Nicholas and Elizabeth Slezak Super Center for Cardiac Research and Biomedical Engineering
Ariel University


    • CFD
    • Coronary stenosis
    • TAG
    • lumped model
    • stenosis severity


    Dive into the research topics of 'Estimation of coronary stenosis severity based on flow distribution ratios'. Together they form a unique fingerprint.

    Cite this