TY - JOUR
T1 - Establishment of a human T-acute lymphoblastic leukemia cell line with a (16;20) chromosome translocation
AU - Ben-Bassat, Hannah
AU - Shlomai, Zipora
AU - Kohn, Gertrude
AU - Prokocimer, Miron
N1 - Funding Information:
This work was supported in part by the MJF Foundation and the Paul Erhlich Center for the Study of Normal and Leukemic White Blood Cells.
PY - 1990/10/15
Y1 - 1990/10/15
N2 - A new T-cell line. Loucy, was established from the peripheral blood of a patient with T-cell acute lymphoblastic leukemia (T-ALL). The surface marker analysis of the cell line is OKT3+, OKT4+, THB4+, J5±, OKT6-, TdT-, and HLA-DR-. indicating stage IV in T-cell lineage. Karyotype analysis revealed 45,X.5q-,t(16;20)(p12;q13). The translocation between chromosomes 16 and 20 has not been previously detected in ALL. This cell line may be of value in evaluating the role of t(16;20) in the etiology of T-ALL.
AB - A new T-cell line. Loucy, was established from the peripheral blood of a patient with T-cell acute lymphoblastic leukemia (T-ALL). The surface marker analysis of the cell line is OKT3+, OKT4+, THB4+, J5±, OKT6-, TdT-, and HLA-DR-. indicating stage IV in T-cell lineage. Karyotype analysis revealed 45,X.5q-,t(16;20)(p12;q13). The translocation between chromosomes 16 and 20 has not been previously detected in ALL. This cell line may be of value in evaluating the role of t(16;20) in the etiology of T-ALL.
UR - http://www.scopus.com/inward/record.url?scp=0025029018&partnerID=8YFLogxK
U2 - 10.1016/0165-4608(90)90148-4
DO - 10.1016/0165-4608(90)90148-4
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AN - SCOPUS:0025029018
SN - 0165-4608
VL - 49
SP - 241
EP - 248
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 2
ER -
