Establishment of a chemical synthetic lethality screen in cultured human cells

Keyphrases

• Blind Test 33%
• Cell-based 33%
• Cultured Human Cells 100%
• DNA Oligonucleotides 33%
• Dominant Negative 33%
• Double-label 33%
• Drug Screening 33%
• Episomal 66%
• Fluorescence System 33%
• Functional Interaction 33%
• Gene of Interest 100%
• Gene-specific 33%
• Genetic Elements 33%
• Genetic Method 33%
• Genotype 33%
• High-throughput Screening 33%
• Human Cell Lines 33%
• Human Genes 66%
• Interacting Proteins 33%
• Malignant Cells 33%
• Metabolic Inhibitors 33%
• Microtiter Plate 33%
• Plasmid 100%
• Selective Pressure 33%
• Synthetic Lethal 66%
• Synthetic Lethality 100%

Biochemistry, Genetics and Molecular Biology

• Genetics 66%
• Genotyping 33%
• High Throughput Screening 33%
• Oligonucleotide 33%
• Plasmid 100%
• Synthetic Lethality 100%