TY - JOUR
T1 - Establishment in continuous culture of a T‐lymphoid cell line (HD‐Mar) from a patient with Hodgkin's lymphoma
AU - Ben‐Bassat, Hannah
AU - Mitrani‐Rosenbaum, Stella
AU - Gamliel, Haim
AU - Naparstek, Elizabeth
AU - Leizerowitz, Rachel
AU - Korkesh, Aviva
AU - Sagi, Michal
AU - Voss, Ruth
AU - Kohn, Gertrude
AU - Polliack, Aaron
PY - 1980/5/15
Y1 - 1980/5/15
N2 - A new cell line, HD‐Mar, was established from a pleural effusion of a patient with Hodgkin's lymphoma. Formation of E rosettes, sensitivity to anti‐T serum, elevated terminal deoxynucleotidyl transferase activity, presence of T‐cell and the common ALL membrane antigens, morphology, and cytochemical staining indicate that the HD‐Mar line is of thymic derivation. Absence of any immunoglobulin determinants, the lack of EBNA or any other EBV‐associated antigen or function are also characteristics associated with established T‐ cell‐derived lymphoma cell lines. Karyotype analysis indicated a tetraploid origin of the cell line.
AB - A new cell line, HD‐Mar, was established from a pleural effusion of a patient with Hodgkin's lymphoma. Formation of E rosettes, sensitivity to anti‐T serum, elevated terminal deoxynucleotidyl transferase activity, presence of T‐cell and the common ALL membrane antigens, morphology, and cytochemical staining indicate that the HD‐Mar line is of thymic derivation. Absence of any immunoglobulin determinants, the lack of EBNA or any other EBV‐associated antigen or function are also characteristics associated with established T‐ cell‐derived lymphoma cell lines. Karyotype analysis indicated a tetraploid origin of the cell line.
UR - http://www.scopus.com/inward/record.url?scp=0018898653&partnerID=8YFLogxK
U2 - 10.1002/ijc.2910250506
DO - 10.1002/ijc.2910250506
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AN - SCOPUS:0018898653
SN - 0020-7136
VL - 25
SP - 583
EP - 590
JO - International Journal of Cancer
JF - International Journal of Cancer
IS - 5
ER -
