Erratum: Regulation of Atg4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection (PLoS Genetics (2012) 8:10 (e1003007) DOI: 10.1371/journal.pgen.1003007)

Ersheng Kuang, Cheryl Y.M. Okumura, Sharon Sheffy-Levin, Tal Varsano, Vincent Chih-Wen Shu, Jianfei Qi, Ingrid R. Niesman, Huei Jiun Yang, Carlos López-Otín, Wei Yuan Yang, John C. Reed, Limor Broday, Victor Nizet, Ze'ev A. Ronai

Research output: Contribution to journalComment/debate

Abstract

After this article [1] was published, concerns were raised about similarities between two pairs of panels in Fig 4: • In Fig 4A, the first and second panels in the left column (GFP::LGG-1) appear similar. • In Fig 4B, the first and fourth panels in the right column (rnf-5(RNAi)) appear similar. The authors noted that these panels were duplicated due to errors in figure preparation. An updated version of Fig 4 is provided here in which the duplicates are removed. The original image files supporting the updated figure are available upon request from the corresponding author. The following images have also been removed in the updated figure: the second panel in right column of Fig 4A, the fourth panel in left column of Fig 4B, the third panel in left column of Fig 4C, and the fourth panel in right column of Fig 4C. These panels were correctly reported in the original figure but were removed in the revised version in order to balance the presentation of control and experimental images. As noted in the figure legend, the images shown in Fig 4 are representative examples of worms harboring the reported changes. The authors confirm that the quantitative results shown in Fig 4A and 4B are unaffected by the image duplication errors. The quantitative data underlying the graphs in Fig 4A and 4C are provided in S1 and S2 Files. The raw quantitative data supporting Fig 4B are not available, for which the authors sincerely apologize. Notably, a set of independent experiments reveal the same pattern shown for Fig 4B (S3 File). (Figure Presented).

Original languageEnglish
Article numbere1008795
JournalPLoS Genetics
Volume16
Issue number5
DOIs
StatePublished - May 2020

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