Erratum: Efficient targeted degradation via reversible and irreversible covalent PROTACs (Journal American Chemical Society (2020) DOI: 10.1021/jacs.9b13907)

Ronen Gabizon, Amit Shraga, Paul Gehrtz, Ella Livnah, Yamit Shorer, Neta Gurwicz, Liat Avram, Tamar Unger, Hila Aharoni, Shira Albeck, Alexander Brandis, Ziv Shulman, Ben Zion Katz, Yair Herishanu, Nir London

Research output: Contribution to journalComment/debate

9 Scopus citations

Abstract

His addition corrects several errors in the chemical drawings in the article. The correction has no influence on the data or conclusions of the work. The configuration of the chiral carbon in Figure 1 in the main text was originally drawn as S. The corrected figure shown here depicts the R enantiomer used in this work. In the Supporting Information PDF files, the configuration of the chiral carbon of the BTK binder in supplementary Table 1 (page S9), supplementary Figure 4 (page S13), and several of the synthetic schemes (pages S17−S42) was originally drawn and marked as S by error. The corrected supplementary file depicts the R enantiomer, which was the sole enantiomer used in the work. The linker in the right panel of supplementary Table 1 (page S9) was missing two carbons in the drawing, and the linker size written for compound PG15 (RC-0b) in the table was incorrect. The corrected supplementary file contains the correct drawings and linker sizes.

Original languageEnglish
Pages (from-to)11316
Number of pages1
JournalJournal of the American Chemical Society
Volume142
Issue number25
DOIs
StatePublished - 24 Jun 2020

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