Eppur Si Muove: Vitamin D is essential in preventing and modulating SLE

S. Azrielant, Y. Shoenfeld*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations

Abstract

Systemic lupus erythematosus (abbreviated SLE or lupus) is a systemic autoimmune disease, with genetic, immunologic, hormonal, and environmental factors. 1 One of the environmental factors that has been studied over the years is vitamin D, which is created in the human body in response to exposure to sunlight and ultraviolet (UV) radiation. This review aims at examining findings from recent years, specifically 2013-2014, regarding the relationship between vitamin D deficiency and SLE flares, severity, and clinical manifestation, as well as to examine the treatment options derived from this relationship.

Original languageEnglish
Pages (from-to)563-572
Number of pages10
JournalLupus
Volume25
Issue number6
DOIs
StatePublished - May 2016

Keywords

  • APS
  • SLE
  • UV light
  • Vitamin D
  • estrogens
  • tolerance

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