Epiretinal proliferation after rhegmatogenous retinal detachment

Moritz Pettenkofer*, Ismael Chehaibou, Cameron Pole, Mercedes Rodriguez, Gilad Rabina, Allan E. Kreiger, Steven D. Schwartz, Jean Pierre Hubschman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To determine the characteristics and appearance rate of epiretinal proliferation (ERP) on SD-OCT after surgery for rhegmatogenous retinal detachment (RRD) repair. Methods: One hundred eight eyes of 108 patients who underwent one or more surgeries for RRD were enrolled. The eyes with other maculopathies that were directly related to RRD were excluded. Image acquisition was performed with SD-OCT (Heidelberg Engineering, Germany). Clinical charts were reviewed to assess clinical and surgical findings. Statistical analyses were performed using XLSTAT (Assinsoft, Paris, France). Results: ERP was found in 9.3% eyes (n = 10). The mean initial visual acuity (logMAR) was 1.34 ± 0.82 in the ERP group compared to 0.49 ± 0.70 in the non-ERP group. PVR was present in 70.0% and chronic macular edema was found in 80.0% of eyes which developed ERP. The mean number of vitreoretinal surgeries in eyes with ERP was 3.3 ± 1.19 and only 1.44 ± 1.02 in eyes without. Silicone oil was used in 60.0% of eyes which developed ERP compared to 13.9% in the non-ERP group. Conclusion: ERP is a late-onset postoperative finding in eyes with RRD and can occur in absence of macular holes. Overall, ERP is more frequent in eyes with complicated courses of RRD including multiple operations, PVR, usage of silicone oil, and chronic macular edema.

Original languageEnglish
Pages (from-to)1509-1516
Number of pages8
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume260
Issue number5
DOIs
StatePublished - May 2022

Funding

FundersFunder number
Research to Prevent Blindness
Ellen, Walter and Lennart Hesselman Foundation for Scientific Research

    Keywords

    • Epiretinal membrane
    • Epiretinal proliferation
    • Macula
    • Müller cells
    • Postoperative complication
    • Proliferative vitreoretinopathy
    • Retina
    • Rhegmatogenous retinal detachment
    • Surgical retina
    • Vitrectomy

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