Epileptische Anfälle und Epilepsie nach einem Schlaganfall: Inzidenz, Prävention und Behandlung

Translated title of the contribution: Epileptic seizures and epilepsy after a stroke: Incidence, prevention and treatment

F. Benninger, M. Holtkamp

Research output: Contribution to journalArticlepeer-review

Abstract

Following stroke, 3–6% of patients develop acute symptomatic seizures within the first 7 days. The rate is higher after cerebral haemorrhage compared to ischaemia. In 10–12% of patients, after more than 7 days unprovoked seizures occur. Due to these low incidence rates, primary prophylaxis with antiepileptic drugs is generally not necessary. Following one acute symptomatic seizure, recurrence risk within the first 7 days post-stroke is 10–20%, generally arguing against secondary prophylaxis with an antiepileptic drug. In clinical practice however, antiepileptic drug treatment in this constellation is often initiated. If this is done, the antiepileptic drug should be withdrawn soon after the acute phase, as the long-term risk for manifestation of an unprovoked seizure is approximately 30%. Following one post-stroke unprovoked seizure, recurrence risk within the next 10 years is more than 70%, this defines epilepsy. In this case, antiepileptic drug treatment is regularly recommended.

Translated title of the contributionEpileptic seizures and epilepsy after a stroke: Incidence, prevention and treatment
Original languageGerman
Pages (from-to)1197-1207
Number of pages11
JournalDer Nervenarzt
Volume88
Issue number10
DOIs
StatePublished - 1 Oct 2017

Keywords

  • Acute symptomatic seizure
  • Antiepileptic drug treatment
  • Primary prophylaxis
  • Secondary prophylaxis
  • Unprovoked seizure

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