Epilepsy surgery in tuberous sclerosis complex (TSC): emerging techniques and redefinition of treatment goals

Jeffrey M. Treiber; Daniel J. Curry; Howard L. Weiner; Jonathan Roth

doi:10.1007/s00381-020-04715-2

Epilepsy surgery in tuberous sclerosis complex (TSC): emerging techniques and redefinition of treatment goals

Jeffrey M. Treiber, Daniel J. Curry, Howard L. Weiner^*, Jonathan Roth

^*Corresponding author for this work

Neurology & Neurosurgery

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Epilepsy occurs in nearly all patients with tuberous sclerosis and is often refractory to medical treatment. The definition of surgical candidacy in these patients has broadened in recent years due to philosophical and technological advances. The goals of surgery have shifted to focusing on quality of life and maximizing neurodevelopmental potential in patients unable to obtain seizure freedom. Novel diagnostic, ablative, and neuromodulatory techniques have been developed that may help patients that were previously considered inoperable to have an improved quality of life. In the coming years, it is expected that these techniques will be further refined and lead to an improvement of neurological prognosis in patients with tuberous sclerosis.

Original language	English
Pages (from-to)	2519-2525
Number of pages	7
Journal	Child's Nervous System
Volume	36
Issue number	10
DOIs	https://doi.org/10.1007/s00381-020-04715-2
State	Published - 1 Oct 2020

Keywords

Epilepsy
Laser ablation
Stereo EEG
Surgery
Tuberous sclerosis

Access to Document

10.1007/s00381-020-04715-2

Cite this

@article{f8180e105973413dae8225816ec6ecca,

title = "Epilepsy surgery in tuberous sclerosis complex (TSC): emerging techniques and redefinition of treatment goals",

abstract = "Epilepsy occurs in nearly all patients with tuberous sclerosis and is often refractory to medical treatment. The definition of surgical candidacy in these patients has broadened in recent years due to philosophical and technological advances. The goals of surgery have shifted to focusing on quality of life and maximizing neurodevelopmental potential in patients unable to obtain seizure freedom. Novel diagnostic, ablative, and neuromodulatory techniques have been developed that may help patients that were previously considered inoperable to have an improved quality of life. In the coming years, it is expected that these techniques will be further refined and lead to an improvement of neurological prognosis in patients with tuberous sclerosis.",

keywords = "Epilepsy, Laser ablation, Stereo EEG, Surgery, Tuberous sclerosis",

author = "Treiber, {Jeffrey M.} and Curry, {Daniel J.} and Weiner, {Howard L.} and Jonathan Roth",

note = "Publisher Copyright: {\textcopyright} 2020, Springer-Verlag GmbH Germany, part of Springer Nature.",

year = "2020",

month = oct,

day = "1",

doi = "10.1007/s00381-020-04715-2",

language = "אנגלית",

volume = "36",

pages = "2519--2525",

journal = "Child's Nervous System",

issn = "0256-7040",

publisher = "Springer Verlag",

number = "10",

}

TY - JOUR

T1 - Epilepsy surgery in tuberous sclerosis complex (TSC)

T2 - emerging techniques and redefinition of treatment goals

AU - Treiber, Jeffrey M.

AU - Curry, Daniel J.

AU - Weiner, Howard L.

AU - Roth, Jonathan

PY - 2020/10/1

Y1 - 2020/10/1

N2 - Epilepsy occurs in nearly all patients with tuberous sclerosis and is often refractory to medical treatment. The definition of surgical candidacy in these patients has broadened in recent years due to philosophical and technological advances. The goals of surgery have shifted to focusing on quality of life and maximizing neurodevelopmental potential in patients unable to obtain seizure freedom. Novel diagnostic, ablative, and neuromodulatory techniques have been developed that may help patients that were previously considered inoperable to have an improved quality of life. In the coming years, it is expected that these techniques will be further refined and lead to an improvement of neurological prognosis in patients with tuberous sclerosis.

AB - Epilepsy occurs in nearly all patients with tuberous sclerosis and is often refractory to medical treatment. The definition of surgical candidacy in these patients has broadened in recent years due to philosophical and technological advances. The goals of surgery have shifted to focusing on quality of life and maximizing neurodevelopmental potential in patients unable to obtain seizure freedom. Novel diagnostic, ablative, and neuromodulatory techniques have been developed that may help patients that were previously considered inoperable to have an improved quality of life. In the coming years, it is expected that these techniques will be further refined and lead to an improvement of neurological prognosis in patients with tuberous sclerosis.

KW - Epilepsy

KW - Laser ablation

KW - Stereo EEG

KW - Surgery

KW - Tuberous sclerosis

UR - http://www.scopus.com/inward/record.url?scp=85086428628&partnerID=8YFLogxK

U2 - 10.1007/s00381-020-04715-2

DO - 10.1007/s00381-020-04715-2

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 32535771

AN - SCOPUS:85086428628

SN - 0256-7040

VL - 36

SP - 2519

EP - 2525

JO - Child's Nervous System

JF - Child's Nervous System

IS - 10

ER -

Epilepsy surgery in tuberous sclerosis complex (TSC): emerging techniques and redefinition of treatment goals

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this