Epilepsy surgery in children compared to adults

Hila Hindi-Ling*, Svetlana Kipervasser, Miri Y. Neufeld, Fani Andelman, Sari Nagar, Vladimir Chistik, Igor Veshchev, Itzhak Fried, Uri Kramer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: The purpose of this study was to compare the frequency of various surgical techniques and surgical outcome between pediatric and adult populations that underwent epilepsy surgery by the same team.Methods: All patients who underwent epilepsy surgery at the Tel Aviv Medical Center between 1997 and 2006 and had been followed up for >2 years were eligible for this study. The majority (90%) of all epilepsy surgeries carried out in Israel were performed in this institution and by a single neurosurgeon. Only patients that underwent video-EEG monitoring as part of the presurgical evaluation were included in the study. Results: A total of 186 patients (131 adults and 55 children) underwent epilepsy surgery in our institute during the study period, and follow-up was available for 177 patients (95%). While the adults underwent significantly more temporal lobe resections (51 vs. 20%, p < 0.0001), the children had significantly more extra-temporal non-lesional resections (18 vs. 1%, p < 0.0001) and hemispherectomies (5 vs. 1%, p = 0.002). Over one half (54%) of all the patients had a postoperative reduction in seizures of >90%, and 72% had a reduction of >50%, with no group difference in surgical success. Among the lesionectomies, the outcome was better for tumors, especially those in the temporal lobe. Only 1% of the patients had a long-term neurological deficit.Conclusions: Children comprised 30% of the epilepsy surgical cases during the study period. Children underwent more non-lesional resections and hemispherectomies, while adults underwent more temporal lobe resections. There was no age-related difference in surgical outcome.

Original languageEnglish
Pages (from-to)180-185
Number of pages6
JournalPediatric Neurosurgery
Volume47
Issue number3
DOIs
StatePublished - Jan 2012

Keywords

  • Children
  • Epilepsy
  • Surgery

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