Epigenetic changes are induced following exposure of peripheral blood cells to CW 800MHz radiation

Rafi Korenstein; Ronit Mazor; Alex Barbul; Avital Korenstein-Ilan

doi:10.1109/URSIGASS.2011.6051342

Epigenetic changes are induced following exposure of peripheral blood cells to CW 800MHz radiation

Rafi Korenstein^*, Ronit Mazor, Alex Barbul, Avital Korenstein-Ilan

^*Corresponding author for this work

Physiology Pharmacology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Genetic and epigenetic changes are involved in initiation and progression of cancer. We exposed peripheral blood cells from young male volunteers to CW 800MHz radiation at SAR values of 2.9 and 4.1 W/kg for 24 hours (n=5) and 72 hours (n=10). Control experiments were carried out in the temperature range of 33.5-40°C. Epigenetic changes were monitored by analysis of FISH patterns of centromeres of chromosomes 11 and 17 reflecting alteration in their replication timing and synchrony. Our results demonstrate radiation induced non-thermal effect on the level of asynchronous replication in both chromosomes following exposure to the higher SAR level.

Original language	English
Title of host publication	2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011
DOIs	https://doi.org/10.1109/URSIGASS.2011.6051342
State	Published - 2011
Event	2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011 - Istanbul, Turkey Duration: 13 Aug 2011 → 20 Aug 2011

Publication series

Name	2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011

Conference

Conference	2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011
Country/Territory	Turkey
City	Istanbul
Period	13/08/11 → 20/08/11

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10.1109/URSIGASS.2011.6051342

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Korenstein, R., Mazor, R., Barbul, A., & Korenstein-Ilan, A. (2011). Epigenetic changes are induced following exposure of peripheral blood cells to CW 800MHz radiation. In 2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011 Article 6051342 (2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011). https://doi.org/10.1109/URSIGASS.2011.6051342

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title = "Epigenetic changes are induced following exposure of peripheral blood cells to CW 800MHz radiation",

abstract = "Genetic and epigenetic changes are involved in initiation and progression of cancer. We exposed peripheral blood cells from young male volunteers to CW 800MHz radiation at SAR values of 2.9 and 4.1 W/kg for 24 hours (n=5) and 72 hours (n=10). Control experiments were carried out in the temperature range of 33.5-40°C. Epigenetic changes were monitored by analysis of FISH patterns of centromeres of chromosomes 11 and 17 reflecting alteration in their replication timing and synchrony. Our results demonstrate radiation induced non-thermal effect on the level of asynchronous replication in both chromosomes following exposure to the higher SAR level.",

author = "Rafi Korenstein and Ronit Mazor and Alex Barbul and Avital Korenstein-Ilan",

year = "2011",

doi = "10.1109/URSIGASS.2011.6051342",

language = "אנגלית",

isbn = "9781424451173",

series = "2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011",

booktitle = "2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011",

note = "2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011 ; Conference date: 13-08-2011 Through 20-08-2011",

}

Korenstein, R, Mazor, R, Barbul, A & Korenstein-Ilan, A 2011, Epigenetic changes are induced following exposure of peripheral blood cells to CW 800MHz radiation. in 2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011., 6051342, 2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011, 2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011, Istanbul, Turkey, 13/08/11. https://doi.org/10.1109/URSIGASS.2011.6051342

Epigenetic changes are induced following exposure of peripheral blood cells to CW 800MHz radiation. / Korenstein, Rafi; Mazor, Ronit; Barbul, Alex et al.
2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011. 2011. 6051342 (2011 30th URSI General Assembly and Scientific Symposium, URSIGASS 2011).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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N2 - Genetic and epigenetic changes are involved in initiation and progression of cancer. We exposed peripheral blood cells from young male volunteers to CW 800MHz radiation at SAR values of 2.9 and 4.1 W/kg for 24 hours (n=5) and 72 hours (n=10). Control experiments were carried out in the temperature range of 33.5-40°C. Epigenetic changes were monitored by analysis of FISH patterns of centromeres of chromosomes 11 and 17 reflecting alteration in their replication timing and synchrony. Our results demonstrate radiation induced non-thermal effect on the level of asynchronous replication in both chromosomes following exposure to the higher SAR level.

AB - Genetic and epigenetic changes are involved in initiation and progression of cancer. We exposed peripheral blood cells from young male volunteers to CW 800MHz radiation at SAR values of 2.9 and 4.1 W/kg for 24 hours (n=5) and 72 hours (n=10). Control experiments were carried out in the temperature range of 33.5-40°C. Epigenetic changes were monitored by analysis of FISH patterns of centromeres of chromosomes 11 and 17 reflecting alteration in their replication timing and synchrony. Our results demonstrate radiation induced non-thermal effect on the level of asynchronous replication in both chromosomes following exposure to the higher SAR level.

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Y2 - 13 August 2011 through 20 August 2011

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Epigenetic changes are induced following exposure of peripheral blood cells to CW 800MHz radiation

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